From Chapter 3:
Thomas Dekker, to whose pictures of London social life at the opening of the seventeenth century we are so much indebted for information both with regard to smoking and in respect of many other matters of interest, was himself an enemy of tobacco. He politely refers to "that great Tobacconist, the Prince of Smoake and Darkness, Don Pluto"; and in another place addresses tobacco as "thou beggarly Monarche of Indians, and setter up of rotten-lungd chimney-sweepers," and proceeds in a like strain of abuse.

From Chapter 5:
The belief in the prophylactic power of tobacco was, however, very generally held. When Mr. Samuel Pepys on June 7, 1665, for the first time saw several houses marked with the ominous red cross, and the words "Lord, have mercy upon us" chalked upon the doors, he felt so ill at ease that he was obliged to buy some roll tobacco to smell and chew. There is nothing to show that Pepys even smoked, which considering his proficiency in the arts of good-fellowship, is perhaps a little surprising. Defoe, in his fictitious but graphic "Journal of the Plague Year in London," says that the sexton of one of the London parishes, who personally handled a large number of the victims, never had the distemper at all, but lived about twenty years after it, and was sexton of the parish to the time of his death. This man, according to Defoe, "never used any preservative against the infection other than holding garlic and rue in his mouth, and smoking tobacco."