From Chapter 1:
"Tarlton, as other gentlemen used, at the first comming up of tobacco, did take it more for fashion's sake than otherwise, and being in a roome, set between two men overcome with wine, and they never seeing the like, wondered at it, and seeing the vapour come out of Tarlton's nose, cryed out, fire, fire, and threw a cup of wine in Tarlton's face. Make no more stirre, quoth Tarlton, the fire is quenched: if the sheriffes come, it will turne to a fine, as the custome is. And drinking that againe, fie, sayes the other, what a stinke it makes; I am almost poysoned. If it offend, saies Tarlton, let every one take a little of the smell, and so the savour will quickly goe: but tobacco whiffes made them leave him to pay all."

From Chapter 7:
There is no mention of Parson Trulliber's pipe, but that pig-breeder and lover can hardly have been a non-smoker. Both the other clerical characters who appear in the book, the Roman Catholic priest who makes an equivocal appearance in the eighth chapter of the third book, and Parson Barnabas, who thinks that his own sermons are at least equal to Tillotson's, smoke their pipes. The other smokers in "Joseph Andrews" are the surgeon and the exciseman who, early in the story, are found sitting in the inn kitchen with Parson Barnabas, "smoking their pipes over some syderand"—the mysterious "cup" being a mixture of cider and something spirituous—and Joseph's father, old Gaffer Andrews, who appears at the end of the story, and complains bitterly that he wants his pipe, not having had a whiff that morning.