From Chapter 1:
In this "Report" Hariot says of the tobacco plant: "There is an herbe which is sowed a part by itselfe and is called by the inhabitants Vppówoc: In the West Indies it hath divers names, according to the severall places and countries where it groweth and is used: The Spaniardes generally call it Tobacco. The leaves thereof being dried and brought into powder: they use to take the fume or smoke thereof by sucking it through pipes made of claie into their stomacke and heade: from whence it purgeth superfluous fleame and other grosse humors, openeth all the pores and passages of the body: by which meanes the use thereof, not only preserveth the body from obstructions: but if also any be, so that they have not beane of too long continuance, in short time breaketh them: wherby their bodies are notably preserved in health, and know not many greevous diseases wherewithall wee in England are oftentimes afflicted."

From Chapter 6:
Other well-known men of the late seventeenth century were "tobacconists" in the old sense of the word. Sir Isaac Newton is said to have smoked immoderately; and a familiar anecdote represents him as using for the purposes of a tobacco-stopper, in a fit of absent-mindedness, the little finger of a lady sitting beside him, whom he admired, but the truth of this legend is open to doubt. Thomas Hobbes, who lived to be ninety (1588-1679), was accustomed to dine at 11 o'clock, after which he smoked a pipe and then lay down and took a nap of about half an hour. No doubt he would have attributed the length of his days to the regularity of his habits. Izaak Walton, who also lived to be ninety, as the lover of the placid and contemplative life deserved to do, loved his pipe, though he seldom mentions smoking in the "Compleat Angler." Sir Samuel Garth, poet and physician, once known to fame as the author of "The Dispensary," was another pipe-lover, as is shown by his verses quoted at the head of this chapter. Dudley, the fourth Lord North, began to smoke in 1657, and, says Dr. Jessopp, "the habit grew upon him, the frequent entries for pipes and tobacco showing that he became more and more addicted to this indulgence. Probably it afforded him some solace in the dreadful malady from which he suffered so long."