From Chapter 2:
When Robert, Earl of Essex, and Henry, Earl of Southampton, were tried for high treason in Westminster Hall on February 19, 1600-1, the members of the House of Lords, who with the Judges formed the Court, if we may believe the French Ambassador of the time, behaved in a remarkable and unseemly manner. In a letter to Monsieur de Rohan, the Ambassador declared that while the Earls and the Counsel were pleading, their lordships guzzled and smoked; and that when they gave their votes condemning the two Earls, they were stupid with eating and "yvres de tabac"—drunk with smoking. This was probably quite untrue as a representation of what actually took place; but it would hardly have been written had smoking not been a common practice among noble lords.

From Chapter Chapter 8:
Cowper then goes on to attack tobacco in lines which show how unpopular smoking at that date was with ladies, and which have since often been quoted by anti-tobacconists with grateful appreciation:

Pernicious weed! whose scent the fair annoys,
Unfriendly to society's chief joys,
Thy worst effect is banishing for hours
The sex whose presence civilizes ours;
Thou art indeed the drug a gardener wants,
To poison vermin that infest his plants,
But are we so to wit and beauty blind,
As to despise the glory of our kind,
And show the softest minds and fairest forms
As little mercy as the grubs and worms?

Notwithstanding this "satiric wipe," it is not likely that Cowper would have had much sympathy with John Wesley, who, in his detestation of what had been his father's solace at Epworth, forbade his preachers either to smoke or to take snuff.