From Chapter 1:
The only mention made of tobacco by Raleigh himself occurs in a testamentary note made a little while before his execution in 1618. Referring to the tobacco remaining on his ship after his last voyage, he wrote: "Sir Lewis Stukely sold all the tobacco at Plimouth of which, for the most part of it, I gave him a fift part of it, as also a role for my Lord Admirall and a role for himself ... I desire that hee may give his account for the tobacco." As showing how closely Sir Walter's name was associated with it long after his death, Dr. Brushfield quotes the following entry from the diary of the great Earl of Cork: "Sept. 1, 1641. Sent by Travers to my infirme cozen Roger Vaghan, a pott of Sir Walter Raleighes tobackoe."

From Chapter 5:
The belief in the prophylactic power of tobacco was, however, very generally held. When Mr. Samuel Pepys on June 7, 1665, for the first time saw several houses marked with the ominous red cross, and the words "Lord, have mercy upon us" chalked upon the doors, he felt so ill at ease that he was obliged to buy some roll tobacco to smell and chew. There is nothing to show that Pepys even smoked, which considering his proficiency in the arts of good-fellowship, is perhaps a little surprising. Defoe, in his fictitious but graphic "Journal of the Plague Year in London," says that the sexton of one of the London parishes, who personally handled a large number of the victims, never had the distemper at all, but lived about twenty years after it, and was sexton of the parish to the time of his death. This man, according to Defoe, "never used any preservative against the infection other than holding garlic and rue in his mouth, and smoking tobacco."