From Chapter 1:
"Tarlton, as other gentlemen used, at the first comming up of tobacco, did take it more for fashion's sake than otherwise, and being in a roome, set between two men overcome with wine, and they never seeing the like, wondered at it, and seeing the vapour come out of Tarlton's nose, cryed out, fire, fire, and threw a cup of wine in Tarlton's face. Make no more stirre, quoth Tarlton, the fire is quenched: if the sheriffes come, it will turne to a fine, as the custome is. And drinking that againe, fie, sayes the other, what a stinke it makes; I am almost poysoned. If it offend, saies Tarlton, let every one take a little of the smell, and so the savour will quickly goe: but tobacco whiffes made them leave him to pay all."

From Chapter 5:
His Majesty was pleased, however, in a letter to Cambridge University, officially to condemn smoking by parsons, as at the same time he condemned the practice of wig-wearing and of sermon-reading by the clergy. But the royal frown was without effect. Wigs soon covered nearly every clerical head from the bench of bishops downwards; and it is very doubtful indeed whether a single parson put his pipe out.