From Chapter 1:
Perhaps the most likely scene of Raleigh's first experiments in the art of smoking was Durham House, which stood where the Adelphi Terrace and the streets between it and the Strand now stand. This was in the occupation of Sir Walter for twenty years (1583-1603), and he was probably resident there when Hariot returned from Virginia to make his report and instruct his employer in the management of a pipe. Walter Thornbury, in his "Haunted London," referring to the story of the servant throwing the ale over his smoking master, says: "There is a doubtful old legend about Raleigh's first pipe, the scene of which may be not unfairly laid at Durham House, where Raleigh lived." The ale story is mythical, but it is highly probable that Sir Walter's first pipes were smoked in Durham House. Dr. Brushfield quotes Hepworth Dixon, in "Her Majesty's Tower," as drawing "an imaginary and yet probable picture of him and his companions at a window of this very house, overlooking the 'silent highway':

From Chapter 5:
Tobacco was still the symbol of good-fellowship. Winstanley, who was an enemy of what he called "this Heathenish Weed," and who thought the "folly" of smoking might never have spread so much if stringent "means of prevention" had been exercised, yet had to declare in 1660 that "Tobacco it self is by few taken now as medicinal, it is grown a good-fellow, and fallen from a Physician to a Complement. 'He's no good-fellow that's without ... burnt Pipes, Tobacco, and his Tinder-Box.'"