From Chapter 3:
"A Tobacco-Seller," says Earle, "is the onely man that findes good in it which others brag of, but do not; for it is meate, drinke, and clothes to him. No man opens his ware with greater seriousnesse, or challenges your judgement more in the approbation. His shop is the Randevous of spitting, where men dialogue with their noses, and their communication is smoake. It is the place onely where Spaine is commended, and prefer'd before England itselfe. He should be well experienc'd in the world: for he ha's daily tryall of mens nostrils, and none is better acquainted with humors. Hee is the piecing commonly of some other trade which is bawde to his Tobacco, and that to his wife, which is the flame that follows this smoke."

From Chapter 5:
Among the many medicinal virtues attributed to tobacco was its supposed value as a preservative from contagion at times of plague. Hearne, the antiquary, writing early in 1721, said that he had been told that in the Great Plague of London of 1665 none of those who kept tobacconists' shops suffered from it, and this belief no doubt enhanced the medical reputation of the weed. I have also seen it stated that during the cholera epidemics of 1831, 1849, and 1866 not one London tobacconist died from that disease; but good authority for the statement seems to be lacking. Hutton, in his "History of Derby," says that when that town was visited by the plague in 1665, that at the "Headless-cross ... the market-people, having their mouths primed with tobacco as a preservative, brought their provisions.... It was observed, that this cruel affliction never attempted the premises of a tobacconist, a tanner or a shoemaker." Whatever ground there may have been for the belief in the prophylactic effect of smoking, there can be no doubt that in the seventeenth century it was firmly held. Howell in one of his "Familiar Letters" dated January 1, 1646, says that the smoke of tobacco is "one of the wholesomest sents that is against all contagious airs, for it overmasters all other smells, as King James they say found true, when being once a hunting, a showr of rain drave him into a Pigsty for shelter, wher he caus'd a pipe full to Be taken of purpose." But here Mr. Howell is certainly drawing the long-bow. One cannot imagine the author of the "Counterblaste" countenancing the use of tobacco under any circumstances.