From Chapter 2:
Among the general audience of the theatre smoking seems to have been usual also. The anti-tobacconists among those present, few of whom were men, must have suffered by the practice. In that admirable burlesque comedy by Beaumont and Fletcher, "The Knight of the Burning Pestle," 1613, the citizen's wife, addressing herself either to the gallants on the stage, or to her fellow-spectators sitting around her, exclaims: "Fy! This stinking tobacco kills men! Would there were none in England! Now I pray, gentlemen, what good does this stinking tobacco do you? Nothing, I warrant you; make chimneys a' your faces!" But many women viewed tobacco differently, as we shall see in the chapter on "smoking by Women." Moreover, this good woman herself, in the epilogue to the burlesque, invites the gentlemen whom she has before abused for smoking, to come to her house where she will entertain them with "a pottle of wine, and a pipe of tobacco."

From Chapter Chapter 8:
Cowper then goes on to attack tobacco in lines which show how unpopular smoking at that date was with ladies, and which have since often been quoted by anti-tobacconists with grateful appreciation:

Pernicious weed! whose scent the fair annoys,
Unfriendly to society's chief joys,
Thy worst effect is banishing for hours
The sex whose presence civilizes ours;
Thou art indeed the drug a gardener wants,
To poison vermin that infest his plants,
But are we so to wit and beauty blind,
As to despise the glory of our kind,
And show the softest minds and fairest forms
As little mercy as the grubs and worms?

Notwithstanding this "satiric wipe," it is not likely that Cowper would have had much sympathy with John Wesley, who, in his detestation of what had been his father's solace at Epworth, forbade his preachers either to smoke or to take snuff.