From Chapter 1:
But the story was a stock jest long before it was associated with Raleigh. The earliest example of it occurs in the "Jests" attributed to Richard Tarleton, the famous comic performer of the Elizabethan stage, who died in 1588—the year of the Armada. "Tarlton's Jests" appeared in 1611, and the story in question, which is headed "How Tarlton tooke tobacco at the first comming up of it," runs as follows:

From Chapter Chapter 8:
Cowper then goes on to attack tobacco in lines which show how unpopular smoking at that date was with ladies, and which have since often been quoted by anti-tobacconists with grateful appreciation:

Pernicious weed! whose scent the fair annoys,
Unfriendly to society's chief joys,
Thy worst effect is banishing for hours
The sex whose presence civilizes ours;
Thou art indeed the drug a gardener wants,
To poison vermin that infest his plants,
But are we so to wit and beauty blind,
As to despise the glory of our kind,
And show the softest minds and fairest forms
As little mercy as the grubs and worms?

Notwithstanding this "satiric wipe," it is not likely that Cowper would have had much sympathy with John Wesley, who, in his detestation of what had been his father's solace at Epworth, forbade his preachers either to smoke or to take snuff.